François Chung; Regional appearance modeling for model-based image segmentation: Methodological approaches to improve the accuracy of model-based image segmentation; Lambert Academic Publishing (LAP), Saarbrücken, 2011; ISBN: 978-3844322095.
This thesis presents a novel appearance prior for model-based image segmentation. This appearance prior, denoted as Multimodal Prior Appearance Model (MPAM), is built upon an Expectation–Maximization (EM) clustering of intensity profiles with model order selection to automatically select the number of profile classes. Unlike classical approaches based on Principal Component Analysis (PCA), the clustering is considered as regional because intensity profiles are classified for each mesh and not for each vertex. Comparative results on liver profiles from Computed Tomography (CT) images show that MPAM outperforms PCA-based appearance models. Finally, methods for the analysis of lower limb structures from Magnetic Resonance (MR) images are presented. A first part deals with the creation of subject-specific models for kinematic simulations of the lower limbs. In a second part, the performance of statistical models is compared in the context of lower limb bone segmentation when only a small number of datasets is available for training.